SIGMA-ALDRICH
Material Safety Data Sheet
Date Printed: 24/MAY/2005
Date Updated: 14/MAR/2004
Version 1.3
According to 91/155/EEC
Classified as Hazardous according to the criteria of EU Annex 1 and
NOHSC.
1 - Product and Company Information
Product Name SODIUM SELENATE ANHYDROUS SIGMAULTRA
Product Number S8295
Company Sigma-Aldrich Pty, Ltd
Unit 2, 14 Anella Avenue
Castle Hill NSW 1765
Australia
Technical Phone # +61 2 9841 0555
Fax +61 2 9841 0500
Emergency Phone # +61 2 9841 0566
2 - Composition/Information on Ingredients
Product Name CAS # EC no Annex I
Index Number
SODIUM SELENATE 13410-01-0 236-501-8 034-002-00-8
Formula Na2SeO4
Molecular Weight 188.94 AMU
Synonyms Disodium selenate * Natriumseleniat (German) *
Sel-tox SSO2 and SS-20 * Sodium selenate *
Sodium selenium oxide (Na2SeO4)
3 - Hazards Identification
SPECIAL INDICATION OF HAZARDS TO HUMANS AND THE ENVIRONMENT
Toxic by inhalation and if swallowed. Danger of cumulative
effects. Very toxic to aquatic organisms, may cause long-term
adverse effects in the aquatic environment.
4 - First Aid Measures
AFTER INHALATION
If inhaled, remove to fresh air. If not breathing give
artificial respiration. If breathing is difficult, give oxygen.
AFTER SKIN CONTACT
In case of skin contact, flush with copious amounts of water for
at least 15 minutes. Remove contaminated clothing and shoes.
Call a physician.
AFTER EYE CONTACT
In case of contact with eyes, flush with copious amounts of
water for at least 15 minutes. Assure adequate flushing by
separating the eyelids with fingers. Call a physician.
AFTER INGESTION
If swallowed, wash out mouth with water provided person is
conscious. Call a physician immediately.
5 - Fire Fighting Measures
EXTINGUISHING MEDIA
Suitable: Noncombustible. Use extinguishing media appropriate to
surrounding fire conditions.
SPECIAL RISKS
Specific Hazard(s): Emits toxic fumes under fire conditions.
SPECIAL PROTECTIVE EQUIPMENT FOR FIREFIGHTERS
Wear self-contained breathing apparatus and protective clothing
to prevent contact with skin and eyes.
6 - Accidental Release Measures
PERSONAL PRECAUTION PROCEDURES TO BE FOLLOWED IN CASE OF LEAK OR SPILL
Evacuate area.
PROCEDURE(S) OF PERSONAL PRECAUTION(S)
Wear self-contained breathing apparatus, rubber boots, and heavy
rubber gloves.
METHODS FOR CLEANING UP
Sweep up, place in a bag and hold for waste disposal. Avoid
raising dust. Ventilate area and wash spill site after material
pickup is complete.
7 - Handling and Storage
HANDLING
Directions for Safe Handling: Do not breathe dust. Do not get in
eyes, on skin, on clothing. Avoid prolonged or repeated exposure.
STORAGE
Conditions of Storage: Keep tightly closed.
8 - Exposure Controls / Personal Protection
ENGINEERING CONTROLS
Safety shower and eye bath. Use only in a chemical fume hood.
GENERAL HYGIENE MEASURES
Wash contaminated clothing before reuse. Wash thoroughly after
handling.
EXPOSURE LIMITS - DENMARK
Source Type Value
OEL TWA 0.1 mg/m3
EXPOSURE LIMITS - UNITED KINGDOM
Source Type Value
OEL TWA 0.1MG(SE)/M3
PERSONAL PROTECTIVE EQUIPMENT
Respiratory Protection: Government approved respirator.
Hand Protection: Compatible chemical-resistant gloves.
Eye Protection: Chemical safety goggles.
9 - Physical and Chemical Properties
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Appearance Physical State: Solid
Color: White
Property Value At Temperature or Pressure
pH 5.5 - 7.5
BP/BP Range N/A
MP/MP Range N/A
Flash Point N/A
Flammability N/A
Autoignition Temp N/A
Oxidizing Properties N/A
Explosive Properties N/A
Explosion Limits N/A
Vapor Pressure N/A
SG/Density N/A
Partition Coefficient N/A
Viscosity N/A
Vapor Density N/A
Saturated Vapor Conc. N/A
Evaporation Rate N/A
Bulk Density N/A
Decomposition Temp. N/A
Solvent Content N/A
Water Content < 0.1 %
Surface Tension N/A
Conductivity N/A
Miscellaneous Data N/A
Solubility Solubility in Water:0.1 M in H2O, 20掳C
complete, colorless
10 - Stability and Reactivity
STABILITY
Stable: Stable.
Materials to Avoid: Strong oxidizing agents.
HAZARDOUS DECOMPOSITION PRODUCTS
Hazardous Decomposition Products: Selenium/selenium oxides.
HAZARDOUS POLYMERIZATION
Hazardous Polymerization: Will not occur
11 - Toxicological Information
RTECS NUMBER: VS6650000
ACUTE TOXICITY
LD50
Oral
Rat
1.6 mg/kg
LD50
Oral
Rabbit
2.25 mg/kg
SIGNS AND SYMPTOMS OF EXPOSURE
Exposure can cause: Anemia. Stomach pains, vomiting, diarrhea.
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Coughing, chest pains, difficulty in breathing. Acute selenium
poisoning produces central nervous system effects, which include
nervousness, convulsions, and drowsiness. Other signs of
intoxication can include skin eruptions, lassitude,
gastrointestinal distress, teeth that are discolored or decayed,
odorous ("garlic") breath, and partial loss of hair and nails.
Chronic exposure by inhalation can produce symptoms that include
pallor, coating of the tongue, anemia, irritation of the mucosa,
lumbar pain, liver and spleen damage, as well as any of the
other previously mentioned symptoms.
ROUTE OF EXPOSURE
Skin Contact: Causes skin irritation.
Skin Absorption: Toxic if absorbed through skin.
Eye Contact: Causes eye irritation.
Inhalation: Toxic if inhaled. Material is irritating to mucous
membranes and upper respiratory tract.
Ingestion: Toxic if swallowed.
TARGET ORGAN INFORMATION
Central nervous system. Liver. Kidneys. Spleen. G.I. System.
Teeth.
CHRONIC EXPOSURE - CARCINOGEN
Result: This product is or contains a component that is not
classifiable as to its carcinogenicity based on its IARC, ACGIH,
NTP, or EPA classification.
Rat
Route of Application: Oral
Exposure Time: 2Y
Result: Tumorigenic:Carcinogenic by RTECS criteria. Lungs,
Thorax, or Respiration:Tumors. Blood:Leukemia
IARC CARCINOGEN LIST
Rating: Group 3
CHRONIC EXPOSURE - MUTAGEN
Human
10 MMOL/L
Cell Type: fibroblast
Unscheduled DNA synthesis
Human
8 NMOL/L
Cell Type: lymphocyte
Cytogenetic analysis
Rat
100 UMOL/L
Cell Type: liver
Unscheduled DNA synthesis
Mouse
14 MG/KG
Oral
Cytogenetic analysis
CHRONIC EXPOSURE - TERATOGEN
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Species: Mouse
Dose: 14 MG/KG
Route of Application: Oral
Exposure Time: (14D POST)
Result: Specific Developmental Abnormalities: Skin and skin
appendages.
Species: Hamster
Dose: 18894 MG/KG
Route of Application: Oral
Exposure Time: (8D PREG)
Result: Effects on Embryo or Fetus: Fetotoxicity (except death,
e.g., stunted fetus).
CHRONIC EXPOSURE - REPRODUCTIVE HAZARD
Species: Rat
Dose: 26 MG/KG
Route of Application: Oral
Exposure Time: (13W MALE)
Result: Paternal Effects: Spermatogenesis (including genetic
material, sperm morphology,motility, and count).
Species: Mouse
Dose: 60 MG/KG
Route of Application: Oral
Exposure Time: (8-12D PREG)
Result: Effects on Newborn: Viability index (e.g., # alive at
day 4 per # born alive). Effects on Newborn: Growth statistics
(e.g., reduced weight gain).
12 - Ecological Information
No data available.
13 - Disposal Considerations
SUBSTANCE DISPOSAL
Bury in a landfill site approved for the disposal of chemical and
hazardous wastes. Observe all federal, state, and local
environmental regulations.
14 - Transport Information
RID/ADR
UN#: 2630
Class: 6.1
PG: I
Proper Shipping Name: Selenates
IMDG
UN#: 2630
Class: 6.1
PG: I
Proper Shipping Name: Selenates
Marine Pollutant: No
Severe Marine Pollutant: No
IATA
UN#: 2630
Class: 6.1
PG: I
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Proper Shipping Name: Selenates
Inhalation Packing Group I: No
15 - Regulatory Information
CLASSIFICATION AND LABELING ACCORDING TO EU DIRECTIVES
ANNEX I INDEX NUMBER: 034-002-00-8
NOTA: A
INDICATION OF DANGER: T N
Toxic. Dangerous for the environment.
R-PHRASES: 23/25 33 50/53
Toxic by inhalation and if swallowed. Danger of cumulative
effects. Very toxic to aquatic organisms, may cause long-term
adverse effects in the aquatic environment.
S-PHRASES: 20/21 28 45 60 61
When using do not eat, drink, or smoke. After contact with
skin, wash immediately with plenty of soap-suds. In case of
accident or if you feel unwell, seek medical advice immediately
(show the label where possible). This material and its
container must be disposed of as hazardous waste. Avoid release
to the environment. Refer to special instructions/safety data
sheets.
COUNTRY SPECIFIC INFORMATION
Germany
WGK: 2
SWITZERLAND
SWISS POISON CLASS: 1
16 - Other Information
WARRANTY
The above information is believed to be correct but does not
purport to be all inclusive and shall be used only as a guide. The
information in this document is based on the present state of our
knowledge and is applicable to the product with regard to
appropriate safety precautions. It does not represent any
guarantee of the properties of the product. Sigma-Aldrich Inc.,
shall not be held liable for any damage resulting from handling or
from contact with the above product. See reverse side of invoice
or packing slip for additional terms and conditions of sale.
Copyright 2005 Sigma-Aldrich Co. License granted to make unlimited
paper copies for internal use only.
DISCLAIMER
For R&D use only. Not for drug, household or other uses.
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