SYSMEX AMERICA, INC.

                                    One Nelson C. White Parkway

                                    Mundelein, IL 60060

                                    (800) 379-7639

                                                                     24-HOUR EMERGENCY PHONE NUMBER

                                    (847) 996-4559

                                                                        Contact CHEM-TEL at 1-800-255-3924

                                    www.sysmex.com









                        Material Safety Data Sheet

                            CELLPACK-GL (PGL-300A & PGL-310A)

                                    Health      Flammability      Reactivity     Contact



                                       2               0              0             1



                                      1 = Slight, 2 = Moderate, 3 = Severe, 4 = Extreme



1.     PRODUCT IDENTIFICATION

       CELLPACK-GLTM is a diluent intended for In Vitro White Blood Cell analysis on designated Sysmex

       Automated Hematology Analyzers. It is provided in a cardboard cube with a plastic liner.



2.      HAZARDOUS INGREDIENTS

                         Percent                     C.A.S. Number             DOT Status

        Formaldehyde      3.1%                          50-00-0                DOT Class 9 criteria / UN2209 designation

                                                                               Is not applicable to this dilute solution.



        Ethylene Glycol             6.4%                107-21-1               Non-hazardous

            Toxicity Estimate:

            Formaldehyde: Oral rat LD50 25g/kg.

            This value is an extrapolation based on literature references. No animal studies were performed. This

            estimate is based on this 3.1% solution, not on formaldehyde gas or the concentrated solution.

            Ethylene Glycol: Oral Rat LD50 4700 mg/Kg

                             Oral Man LDLo, range from 400 mg/Kg to 1600 mg/Kg

                             Oral Man TDLo, 1.2 to 16 g/Kg



            Carcinogen Data: POTENTIAL CANCER HAZARD

            RTECS

            Formaldehyde: Probable human carcinogen, based on limited evidence in humans and sufficient

            evidence in animals. Human data include nine studies that show statistically significant associations

            between site-specific respiratory neoplasms and exposure to formaldehyde or formaldehyde containing

            products. An increased incidence of nasal squamous cell carcinomas was observed in long-term

            inhalation studies in rats and mice.



            Ethylene Glycol: Not identified as a human carcinogen

            NTP

            Formaldehyde is a substance reasonably anticipated to be a carcinogen.

            IARC

            Formaldehyde has sufficient animal evidence, but inadequate human evidence of carcinogenicity.

            NIOSH

            Sites tumorigenic data and notes carcinogenic status by RTECS criteria.

            EPA

            Group B1 carcinogen based upon limited evidence on humans and animals. Formaldehyde is to be

            considered a probable carcinogen.







CELLPACK-GL (PGL-300A & PGL-310A)                                                                               Page 1 of 2

Reviewed 10/2006

3.        PHYSICAL DATA

          Clear aqueous solution. Pungent odor detected at 0.8 - 1.0 ppm, however prolonged exposure may

          desensitize the olfactory sense. Specific Gravity at 25?C = 1.020. Other physical properties of this solution

          have not been determined but can be expected to approximate water, which is its major component.

4.        FIRE AND EXPLOSION DATA

          CELLPACK-GL is not combustible. However, formaldehyde solutions heated in fire conditions will release

          gaseous formaldehyde, which is flammable and explosive.



               Fire Fighting Procedures: Full protective clothing/NIOSH approved self-contained breathing apparatus

               with full-face piece.

5.        REACTIVITY DATA

          Stable solution. Incompatibility of other chemicals with formaldehyde is not significant under intended use

          conditions.

6.        HEALTH HAZARD DATA

          Potential cancer hazard. Liquid or vapor irritant to eyes, skin, nose, throat and mucous membranes. Eye

          contact may cause severe discomfort and possible injury. Prolonged or repeated skin exposure may result in

          allergic eczematous dermatitis, a hypersensitivity reaction. Ingestion may cause irritation to the mouth, throat

          and stomach, with vomiting, diarrhea and abdominal pain.

          Formaldehyde gas is evolved above the liquid, with time the gas concentration increases. For this reason

          spills must be handled promptly ?see Spills and Disposal Procedures. When this reagent is used in the

          Sysmex NE-Series instrument, there is no measurable environmental discharge of formaldehyde gas.

          Opening and changing reagent cubes or instrument maintenance where reagent contact is possible should

          be performed with good ventilation, wearing gloves, and lab coat. Safety glasses or goggles and liquid

          impervious clothing are suggested if a splash is reasonably anticipated.

             Suggested First Aid Procedures

              Ingestion: Obtain immediate medical attention. If patient is alert, dilute, inactivate by giving, milk,

               activated charcoal, or water. Keep person warm and at rest. If vomiting occurs, turn patient on side and

               keep head lower than hips.

              Inhalation: Move patient to fresh air. Obtain medical advice.

              Skin contact: Remove contaminated clothing. Wash affected area with soap and water.

              Eye Contact: Immediately flush eyes with water, lifting lower and upper lids until all traces of irritation is

               removed. Obtain medical advice.

7.        SPILLS AND DISPOSAL PROCEDURES

          Spills should be neutralized and cleaned up promptly or formaldehyde gas concentration will increase with

          time. Dike, contain and absorb the spill with neutral absorbent material as possible, and if large spill,

          evacuate personnel from the immediate area. Sodium Sulfite may be used to neutralize the formaldehyde,

          this and increased ventilation will reduce exposure to formaldehyde gas. Wear gloves, safety goggles and

          liquid impervious clothing to protect against splash. Respiratory protection may be necessary to avoid

          exposing clean-up crew to levels above the 2.0 ppm STEL. In formaldehyde levels < 7.5 ppm, a half-mask or

          full mask negative pressure respirator with formaldehyde rated cartridges may be used. Place absorbed spill

          in a sealed container for disposal. Label this container: DANGER FORMALDEHYDE, IRRITANT AND

          POTENTIAL CANCER HAZARD. Dispose of waste in accordance with applicable local, state and federal

          regulations.

8.       STORAGE AND SPECIAL INFORMATION

         Store at controlled room temperature away from direct sunlight, to ensure reagent performance.



Sysmex America, Inc. provides the information contained herein in good faith, but makes no representative claim or warranty as to its

completeness or accuracy. This document is intended only as a guide for appropriate handling of the material described by properly trained

persons using the product according to its intended purposes. Individuals receiving this information retain the responsibility for determining the

suitability of the information for any specific purpose. Users should consider these data only as supplement to other information gathered by

themselves and must make independent determinations of the suitability and completeness of information from all sources to ensure proper use

and disposal of these materials and for the safety and health of employees and customers. No warranty, expressed or implied, is made with regard

to such information.



Permission is granted to make unlimited paper copies of this MSDS for internal purposes only.

CELLPACK-GL (PGL-300A & PGL-310A)                                                                                                     Page 2 of 2

Reviewed 10/2006