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MSDS  
:
 1-[(2-Ethyl-4-methyl-1H-imidazol-5-yl)methyl]-4-[5-(trifluoromethyl)-2-pyridinyl]piperazine
CAS  
:
 na
SYNONYMS  
:
 None known.

Section 1 - Chemical Product and Company Identification

Catalog Numbers: HTS06481SC
Synonyms:
None known.
Company Identification:
              Maybridge PLC
              Trevillett, Tintagel
              Cornwall, England. PL34 0HW
For information, call:
+44(0)1840770453
For emergencies, call:
+44(0)7702924616

Section 2 - Composition, Information on Ingredients

CAS# Chemical Name Percent EINECS/ELINCS
na 1-[(2-Ethyl-4-methyl-1H-imidazol-5-yl)methyl]-4-[5-(trifluoromethyl)-2-pyridinyl]piperazine unlisted

Section 3 - Hazards Identification

EMERGENCY OVERVIEW

Appearance: cream solid.
Danger! Causes burns by all exposure routes. Harmful if swallowed, inhaled, or absorbed through the skin.
Target Organs: Respiratory system, gastrointestinal system, eyes, skin.


Potential Health Effects
Eye: Causes eye burns.
Skin: Harmful if absorbed through the skin. Causes skin burns.
Ingestion: Harmful if swallowed. Causes gastrointestinal tract burns.
Inhalation: Harmful if inhaled. Causes chemical burns to the respiratory tract.
Chronic: No information found.

Section 4 - First Aid Measures


Eyes: Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid imme diately.
Skin: Get medical aid immediately. Immediately flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes.
Ingestion: Do not induce vomiting. Get medical aid immediately. Call a poison control center.
Inhalation: Get medical aid immediately. Remove from exposure and move to fresh air immediately. If breathing is difficult, give oxygen. Do not use mouth-to-mouth resuscitation if victim ingested or inhaled the substance; induce artificial respiration with the aid of a pocket mask equipped with a one-way valve or other proper respiratory medical device.
Notes to Physician: Treat symptomatically and supportively.

Section 5 - Fire Fighting Measures


General Information: As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear.
Extinguishing Media: Use foam, dry chemical, or carbon dioxide.
Flash Point: Not available.
Autoignition Temperature: Not available.
Explosion Limits, Lower:Not available.
Upper: Not available.
NFPA Rating: (estimated) Health: 3; Flammability: 1; Instability: 0

Section 6 - Accidental Release Measures


General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks: Vacuum or sweep up material and place into a suitable disposal container. Wear a self contained breathing apparatus and appropriate personal protection. (See Exposure Controls, Personal Protection section). Avoid generating dusty conditions. Provide ventilation. Do not let this chemical enter the environment.

Section 7 - Handling and Storage


Handling: Minimize dust generation and accumulation. Do not get in eyes, on skin, or on clothing. Do not ingest or inhale. Use only in a chemical fume hood.
Storage: Store in a cool, dry place. Store in a tightly closed container. Corrosives area.

Section 8 - Exposure Controls, Personal Protection


Engineering Controls: Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use only under a chemical fume hood.
Exposure Limits
Chemical Name ACGIH NIOSH OSHA - Final PELs
1-[(2-Ethyl-4-methyl-1H-imidazol-5-yl)methyl]-4-[5-(trifluoromethyl)-2-pyridinyl]piperazine none listed none listed none listed

OSHA Vacated PELs: No OSHA Vacated PELs are listed for this chemical.
Personal Protective Equipment
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166.
Skin: Wear appropriate protective gloves to prevent skin exposure.
Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators: Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced.

Section 9 - Physical and Chemical Properties


Physical State: Solid
Appearance: cream
Odor: Not available.
pH: Not available.
Vapor Pressure: Not available.
Vapor Density: Not available.
Evaporation Rate:Not available.
Viscosity: Not available.
Boiling Point: Not available.
Freezing/Melting Point:Not available.
Decomposition Temperature:Not available.
Solubility: Not available.
Specific Gravity/Density:Not available.
Molecular Formula:C17H22F3N5
Molecular Weight:353.39

Section 10 - Stability and Reactivity


Chemical Stability: Stable under normal temperatures and pressures.
Conditions to Avoid: Incompatible materials, dust generation.
Incompatibilities with Other Materials: Strong oxidizing agents, strong reducing agents, strong acids, strong bases.
Hazardous Decomposition Products: Carbon monoxide, oxides of nitrogen, carbon dioxide, hydrogen fluoride gas, fluorine.
Hazardous Polymerization: Has not been reported

Section 11 - Toxicological Information


RTECS#:      
CAS# na unlisted.
LD50/LC50:
Not available.

Carcinogenicity:
CAS# na: Not listed by ACGIH, IARC, NTP, or CA Prop 65.

Epidemiology: No information found
Teratogenicity: No information found
Reproductive Effects: No information found
Mutagenicity: No information found
Neurotoxicity: No information found
Other Studies:

Section 12 - Ecological Information


Ecotoxicity: No data available. No information available.
Environmental: No information available.
Physical: No information available.
Other: Do not empty into drains.

Section 13 - Disposal Considerations

Chemical waste generators must determine whether a discarded chemical is classified as a hazardous waste. US EPA guidelines for the classification determination are listed in 40 CFR Parts 261.3. Additionally, waste generators must consult state and local hazardous waste regulations to ensure complete and accurate classification.
RCRA P-Series: None listed.
RCRA U-Series: None listed.

Section 14 - Transport Information

US DOT Canada TDG
Shipping Name: AMINES, SOLID, CORROSIVE, N.O.S.* AMINES, SOLID, CORROSIVE, N.O.S.*
Hazard Class: 8 8
UN Number: UN3259 UN3259
Packing Group: III III

Section 15 - Regulatory Information

US FEDERAL

TSCA
     CAS# na is not listed on the TSCA inventory. It is for research and development use only.
Health & Safety Reporting List
     None of the chemicals are on the Health & Safety Reporting List.
Chemical Test Rules
     None of the chemicals in this product are under a Chemical Test Rule.
Section 12b
     None of the chemicals are listed under TSCA Section 12b.
TSCA Significant New Use Rule
     None of the chemicals in this material have a SNUR under TSCA.
CERCLA Hazardous Substances and corresponding RQs
     None of the chemicals in this material have an RQ.
SARA Section 302 Extremely Hazardous Substances
     None of the chemicals in this product have a TPQ.
Section 313      No chemicals are reportable under Section 313.
Clean Air Act:
     This material does not contain any hazardous air pollutants.
     This material does not contain any Class 1 Ozone depletors.
     This material does not contain any Class 2 Ozone depletors.
Clean Water Act:
     None of the chemicals in this product are listed as Hazardous Substances under the CWA.
     None of the chemicals in this product are listed as Priority Pollutants under the CWA.
     None of the chemicals in this product are listed as Toxic Pollutants under the CWA.
OSHA:
     None of the chemicals in this product are considered highly hazardous by OSHA.
STATE
     CAS# na is not present on state lists from CA, PA, MN, MA, FL, or NJ.

California Prop 65

California No Significant Risk Level: None of the chemicals in this product are listed.

European/International Regulations

European Labeling in Accordance with EC Directives
Hazard Symbols:
     C
Risk Phrases:

     R 20/21/22 Harmful by inhalation, in contact with skin and if
     swallowed.
     R 34 Causes burns.

Safety Phrases:

     S 22 Do not breathe dust.
     S 26 In case of contact with eyes, rinse immediately with plenty of
     water and seek medical advice.
     S 36/37/39 Wear suitable protective clothing, gloves and eye/face pr
     otection.
     S 45 In case of accident or if you feel unwell, seek medical advice
     immediately (show the label where possible).

WGK (Water Danger/Protection)

     CAS# na: No information available.
Canada - DSL/NDSL
None of the chemicals in this product are listed on the DSL or NDSL list.
Canada - WHMIS
     This product has a WHMIS classification of E, D1B.
This product has been classified in accordance with the hazard criteria of the Controlled Products Regulations and the MSDS contains all of the information required by those regulations.
Canadian Ingredient Disclosure List

Section 16 - Additional Information

MSDS Creation Date: 8/30/2007
Revision #1 Date: 9/04/2007

The information above is believed to be accurate and represents the best information currently available to us. However, we make no warranty of merchantability or any other warranty, express or implied, with respect to such information, and we assume no liability resulting from its use. Users should make their own investigations to determine the suitability of the information for their particular purposes. In no event shall Fisher be liable for any claims, losses, or damages of any third party or for lost profits or any special, indirect, incidental, consequential or exemplary damages, howsoever arising, even if Fisher has been advised of the possibility of such damages.

ALL Chemical Analysis PAGES IN THIS GROUP
NAMECAS
3-[(2-Chloroacetyl)amino]thiophene-2-carboxylic acid 648858-95-1
Ammonium chloride, with anti-caking agent 124-30-1
3-Methyladamantane-1-carboxylic acid 33649-73-9
N-[2-Methyl-5-(piperidinosulfonyl)-3-furyl]-N'-phenylurea na
Tetrahydrothiophen-3-one oxime 24030-02-2
N-Phenethylthieno[3,2-d]pyrimidin-4-amine na
2-{4-[3-Chloro-5-(trifluoromethyl)-2-pyridyl]piperazino}ethan-1-ol 215434-40-5
Pentafluorophenyl 4-morpholinobenzoate 921938-51-4
2-Isocyanato-5-methylthiophene 76536-99-7
3-Phenylisoxazole-5-carbonyl chloride 124953-60-2
2-Chloro-1,3-thiazole-5-carbaldehyde 95453-58-0
4-Methyl-2-pyrid-4-yl-1,3-thiazole-5-carbaldehyde 892502-19-1
N-Methyl-(3-phenylisoxazol-5-yl)methylamine 852431-00-6
6-(Tetrahydropyran-4-yloxy)nicotinaldehyde 910036-95-2
Lithium sulfide, powder 12136-58-2
Citrus Burst? 3 Not available
Citrus Burst? 2 Not available
2-Hydroxyphenylboronic acid 89466-08-0
2-(Methylthio)phenylboronic acid 168618-42-6
N-(3-Chlorophenyl)-N'-[6-chloro-4-(trifluoromethyl)-2-pyridyl]urea na
3,5-Dichlorophenyl isothiocyanate 6590-93-8
1,5-Di(3-bromopropanoyl)-2,3,4,5-tetrahydro-1H-1,5-benzodiazepin-2-one na
Quinine, anhydrous, 99% (titr) 130-95-0
4-(4-Chloro-3-nitrophenyl)-2-(4-fluorophenyl)-1,3-thiazole na
1-(tert-Butoxycarbonyl)piperidine-3-carboxylic acid 84358-12-3
1-(4-Bromobenzyl)piperazine 91345-62-9
Potassium Phosphate, Dibasic Trihydrate, 99+% 16788-57-1
1-Allylpiperazine 13961-36-9
1-(2-Aminoethyl)-4-methylpiperazine 934-98-5
1-[(2-Ethyl-4-methyl-1H-imidazol-5-yl)methyl]-4-[5-(trifluoromethyl)-2-pyridinyl]piperazine na
1,2,3,4,6,7-Hexabromonaphthalene na
N-[3-(4-Chloroanilino)-1H-1,2,4-triazol-5-yl]-N'-isopropylurea na
N-[3-(4-Chloroanilino)-1H-1,2,4-triazol-5-yl]-N'-propylurea na
2-Phenylpyrrolidine 1006-64-0
Methyl 2,3-diaminobenzoate 107582-20-7
Benzyl Methyl Sulfide, 98% 766-92-7
5-Bromopicolinic acid 30766-11-1
2-Methoxy-4-vinylphenol 7786-61-0
1-(Thien-2-ylmethyl)piperidine-4-carboxylic acid hydrochloride hydrate 944450-84-4
Phenyltrifluorosilane 368-47-8
2-Bromo-1-(1-methyl-1H-benzimidazol-5-yl)ethanone hydrobromide 944450-78-6
2-Fluoro-4-picoline 461-87-0
N-Methyl-[(4-bromothien-3-yl)methyl]amine hydrochloride 944450-82-2
2-[1-Methyl-3-(trifluoromethyl)-1H-pyrazol-5-yl]benzylamine 910095-35-1
2,5-Bis(trifluoromethyl)benzaldehyde 395-64-2
(4-Thien-2-yltetrahydropyran-4-yl)methylamine 906422-74-0
3-Hydroxy-5-[2-(trifluoromethyl)anilino]isothiazole-4-carbonitrile na
5-Nitro-2-furaldehyde, 99% 698-63-5
Ethyl 2,3-dibromo-3-phenylpropanoate 5464-70-0
1-(3-Chloro-4-hydroxyphenyl)propan-1-one 2892-27-5



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