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Section 1 - Chemical Product and Company Identification |
MSDS Name: Iodomethane-d3, 99+ atom % D
Catalog Numbers:
AC174950000, AC174950050, AC174950250
Synonyms:
Iodomethane.
Company Identification:
Acros Organics N.V.
One Reagent Lane
Fair Lawn, NJ 07410
For information in North America, call: 800-ACROS-01
For emergencies in the US, call CHEMTREC: 800-424-9300
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Section 2 - Composition, Information on Ingredients
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| CAS# |
Chemical Name |
Percent |
EINECS/ELINCS |
| 865-50-9 |
Iodomethane-d3 |
99 | 212-744-5 |
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Section 3 - Hazards Identification
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EMERGENCY OVERVIEW
Appearance: clear, colorless to pale yellow liquid.
Danger! May be fatal if inhaled. Causes eye, skin,
and respiratory tract irritation. Harmful if swallowed or absorbed
through the skin. Light sensitive. May cause central nervous system
effects.
Target Organs: Central nervous system, lungs,
eyes, skin.
Potential Health Effects
Eye:
Causes eye irritation. Vapors cause eye irritation.
Skin:
Causes skin irritation. Harmful if absorbed through the skin.
A pad soaked in methyl iodide and held against the forearm for 10
minutes produced stinging and reddening; swelling and blistering
appeared several hours later. Similar effects, including delayed
burning, have been reported. When methyl iodide was not held against
the skin, but allowed to evaporate, no effects were observed.
Ingestion:
Harmful if swallowed. May cause irritation of the digestive tract.
May cause effects similar to those for inhalation exposure.
Inhalation:
Causes respiratory tract irritation.
In humans, acute exposure to methyl iodide by inhalation may depress
the central nervous system (CNS), irritate the lungs and skin, and
affect the kidneys. Massive acute inhalation exposure to methyl
iodide has led to pulmonary edema. Acute inhalation exposure of
humans to methyl iodide has resulted in nausea, vomiting, vertigo,
ataxia (failure of muscular coordination), slurred speech,
drowsiness, skin blistering, and eye irritation. Severe, prolonged
and possibly permanent injury to the nervous system (mental
dullness, hallucination) has been reported.
Chronic:
Chronic inhalation may cause effects similar to those of acute
inhalation. Animal studies have reported the development of tumors.
Chronic or long-term exposure of humans to methyl iodide by
inhalation may affect the CNS and cause skin burns. (EPA Air Toxics
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Section 4 - First Aid Measures
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Eyes:
In case of contact, immediately flush eyes with plenty of water for a
t least 15 minutes. Get medical aid.
Skin:
In case of contact, immediately flush skin with plenty of water for
at least 15 minutes while removing contaminated clothing and shoes.
Get medical aid immediately. Wash clothing before reuse.
Ingestion:
If swallowed, do not induce vomiting unless directed to do so by
medical personnel. Never give anything by mouth to an unconscious
person. Get medical aid.
Inhalation:
POISON material. If inhaled, get medical aid immediately. Remove
victim to fresh air. If not breathing, give artificial respiration.
If breathing is difficult, give oxygen.
Notes to Physician:
Treat symptomatically and supportively.
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Section 5 - Fire Fighting Measures
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General Information:
As in any fire, wear a self-contained breathing apparatus in
pressure-demand, MSHA/NIOSH (approved or equivalent), and full
protective gear. During a fire, irritating and highly toxic gases
may be generated by thermal decomposition or combustion. Substance
is noncombustible.
Extinguishing Media:
Use extinguishing media most appropriate for the surrounding fire.
Flash Point: Not applicable.
Autoignition Temperature: Not applicable.
Explosion Limits, Lower:N/A
Upper: N/A
NFPA Rating:
(estimated) Health: 3; Flammability: 0; Instability: 0
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Section 6 - Accidental Release Measures
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General Information: Use proper personal protective equipment as indicated
in Section 8.
Spills/Leaks:
Absorb spill with inert material (e.g. vermiculite, sand or earth),
then place in suitable container. Avoid runoff into storm sewers and
ditches which lead to waterways. Provide ventilation. Evacuate
unnecessary personnel.
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Section 7 - Handling and Storage
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Handling:
Wash thoroughly after handling. Remove contaminated clothing and
wash before reuse. Do not get in eyes, on skin, or on clothing. Do
not breathe vapor. Use only with adequate ventilation or respiratory
protection.
Storage:
Store in a tightly closed container. Store in a cool, dry,
well-ventilated area away from incompatible substances. Store
protected from light. Refrigeration has been recommended.
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Section 8 - Exposure Controls, Personal Protection
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Engineering Controls:
Use process enclosure, local exhaust ventilation, or other
engineering controls to control airborne levels below recommended
exposure limits. Facilities storing or utilizing this material should
be equipped with an eyewash facility and a safety shower.
Exposure Limits
| Chemical Name |
ACGIH |
NIOSH |
OSHA - Final PELs |
| Iodomethane-d3
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none listed
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none listed
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none listed
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| Methyl iodide
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2 ppm TWA; Skin - potential significant contribution to overall exposure by the cutaneous r oute
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2 ppm TWA; 10 mg/m3 TWA 100 ppm IDLH
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5 ppm TWA; 28 mg/m3 TWA
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OSHA Vacated PELs:
Iodomethane-d3:
No OSHA Vacated PELs are listed for this chemical.
Methyl iodide:
2 ppm TWA; 10 mg/m3 TWA
Personal Protective Equipment
Eyes:
Wear chemical splash goggles.
Skin:
Wear appropriate protective gloves to prevent skin
exposure.
Clothing:
Wear appropriate protective clothing to prevent skin
exposure.
Respirators:
Follow the OSHA respirator regulations found in 29
CFR 1910.134 or European Standard EN 149. Use a
NIOSH/MSHA or European Standard EN 149 approved
respirator if exposure limits are exceeded or if
irritation or other symptoms are experienced.
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Section 9 - Physical and Chemical Properties
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Physical State: Liquid
Appearance: clear, colorless to pale yellow
Odor: Sweet, ethereal
pH: Not available.
Vapor Pressure: 375 mm Hg @ 20 deg C
Vapor Density: 4.89 (air = 1)
Evaporation Rate:Not available.
Viscosity: Not available.
Boiling Point: 42 deg C @ 760 mm Hg
Freezing/Melting Point:-66 deg C
Decomposition Temperature:270 deg C
Solubility: 14 g/1000 ml @ 20癈
Specific Gravity/Density:2.28 @ 20癈
Molecular Formula:CD3I
Molecular Weight:144.96
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Section 10 - Stability and Reactivity
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Chemical Stability:
Stable under normal temperatures and pressures. May discolor on
exposure to light. Turns reddish-brown on exposure to light.
Conditions to Avoid:
Light, moisture, excess heat.
Incompatibilities with Other Materials:
Strong oxidizing agents.
Hazardous Decomposition Products:
Carbon monoxide, carbon dioxide, hydrogen iodide, iodide.
Hazardous Polymerization: Will not occur.
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Section 11 - Toxicological Information
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RTECS#:
CAS# 865-50-9
unlisted.
CAS# 74-88-4:
PA9450000
LD50/LC50:
Not available.
CAS# 74-88-4:
Dermal, guinea
pig: LD50 = 800 mg/kg;
Draize test,
rabbit, eye: 100 mg Severe;
Draize
test, rabbit, skin: 500 mg Severe;
Inhalation, mouse: LC50 = 5
gm/m3/57M-C;
Inhalation, mouse:
LC50 = 5000 mg/m3/57M;
Inhalation,
rat: LC50 = 1300 mg/m3/4H;
Oral,
rat: LD50 = 76 mg/kg;
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Carcinogenicity:
CAS# 865-50-9:
Not listed by ACGIH, IARC, NTP, or CA Prop 65.
CAS# 74-88-4:
- ACGIH:
Not listed.
- California:
carcinogen, initial date 4/1/88
- NTP:
Not listed.
- IARC:
Not listed.
Epidemiology:
Because the increase in lung tumors seen in Strain A mice
is not statistically significant, ACGIH recommends that
methyl iodide carry no carcinogenicity notation.
Teratogenicity:
No information available.
Reproductive Effects:
No information available.
Mutagenicity:
Mutation data has been reported.
Neurotoxicity:
No information available.
Other Studies:
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Section 12 - Ecological Information
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Ecotoxicity:
No data available.
No information available.
Environmental:
Naturally produced by photosynthetic marine organisms. On land,
volatilizes rapidly. In atmosphere, degradation half-life is 3-7
hours. Will not bioconcentrate.
Physical:
No information available.
Other:
log octanol/water partition coefficient (log Kow) is 1.51.
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Section 13 - Disposal Considerations
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Chemical waste generators must determine whether a discarded chemical is classified
as a hazardous waste.
US EPA guidelines for the classification determination are listed in 40 CFR Parts 261.3.
Additionally, waste generators must consult state and local hazardous waste regulations to
ensure complete and accurate classification.
RCRA P-Series: None listed.
RCRA U-Series:
CAS# 74-88-4: waste
number U138.
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Section 14 - Transport Information
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US DOT |
Canada TDG |
| Shipping Name: |
METHYL IODIDE |
METHYL IODIDE |
| Hazard Class: |
6.1 |
6.1 |
| UN Number: |
UN2644 |
UN2644 |
| Packing Group: |
I |
I |
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Section 15 - Regulatory Information
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US FEDERAL
TSCA
CAS# 865-50-9 is not listed on the TSCA inventory.
It is for research and development use only.
CAS# 74-88-4 is listed on the TSCA inventory.
Health & Safety Reporting List
None of the chemicals are on the Health & Safety Reporting List.
Chemical Test Rules
None of the chemicals in this product are under a Chemical Test Rule.
Section 12b
None of the chemicals are listed under TSCA Section 12b.
TSCA Significant New Use Rule
None of the chemicals in this material have a SNUR under TSCA.
CERCLA Hazardous Substances and corresponding RQs
CAS# 74-88-4: 100 lb final RQ; 45.4 kg final RQ
SARA Section 302 Extremely Hazardous Substances
None of the chemicals in this product have a TPQ.
SARA Codes
CAS # 74-88-4: immediate, delayed.
Section 313
This material contains Methyl
iodide (CAS# 74-88-4, -%),which is subject to the reporting
requirements of Section 313 of SARA Title III and 40 CFR Part 373.
Clean Air Act:
CAS# 74-88-4 is listed as a hazardous air pollutant (HAP).
This material does not contain any Class 1 Ozone depletors.
This material does not contain any Class 2 Ozone depletors.
Clean Water Act:
None of the chemicals in this product
are listed as Hazardous Substances under the CWA.
None of the chemicals in this
product are listed as Priority Pollutants under the CWA.
None of the chemicals in this
product are listed as Toxic Pollutants under the CWA.
OSHA:
CAS# 74-88-4 is considered highly hazardous by OSHA.
STATE
CAS# 865-50-9 is not present on
state lists from CA, PA, MN, MA, FL, or NJ.
CAS# 74-88-4 can be found on the
following state right to know lists: California, New Jersey,
Pennsylvania, Minnesota, Massachusetts.
California Prop 65
WARNING: This product contains Methyl iodide, a chemical known to
the state of California to cause cancer.
California No Significant Risk Level:
None of the chemicals in this product are listed.
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols:
T
Risk Phrases:
R 21 Harmful in contact with skin.
R 23/25 Toxic by inhalation and if swallowed.
R 37/38 Irritating to respiratory system and skin.
R 40 Limited evidence of a carcinogenic effect.
Safety Phrases:
S 36/37 Wear suitable protective clothing and gloves.
S 38 In case of insufficient ventilation, wear suitable respiratory
equipment.
S 45 In case of accident or if you feel unwell, seek medical advice
immediately (show the label where possible).
WGK (Water Danger/Protection)
CAS# 865-50-9: No information available.
CAS# 74-88-4: 2
Canada - DSL/NDSL
CAS# 74-88-4 is listed on Canada's DSL List.
Canada - WHMIS
This product has a WHMIS classification of D1A, D2B.
This product has been classified in accordance with the hazard
criteria of the Controlled Products Regulations and the MSDS
contains all of the information required by those regulations.
Canadian Ingredient Disclosure List
CAS# 74-88-4 is listed on the Canadian Ingredient Disclosure List.
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Section 16 - Additional Information
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MSDS Creation Date: 9/02/1997
Revision #9 Date: 3/16/2007
The information above is believed to be accurate and represents the best
information currently available to us. However, we make no warranty of
merchantability or any other warranty, express or implied, with respect to
such information, and we assume no liability resulting from its use. Users
should make their own investigations to determine the suitability of the
information for their particular purposes. In no event shall Fisher be liable
for any claims, losses, or damages of any third party or for lost profits
or any special, indirect, incidental, consequential or exemplary
damages, howsoever arising, even if Fisher has been advised of
the possibility of such damages.
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