|
Section 1 - Chemical Product and Company Identification |
MSDS Name: Phenolphthalein
Catalog Numbers:
AC147710000, AC147711000, AC147715000, AC417180000, AC417180025,
AC417181000, AC417185000, S76958, S76961, S93324, P79-100, P79-500, S71428
Synonyms:
3,3-Bis(4-Hydoroxyphenyl)-1(3H)-Isobenzofuranone;
3,3-Bis(p-Hydroxyphenyl)Phthalide; Alpha-Di(p-Hydroxyphenyl)phthalide
Company Identification:
Fisher Scientific
1 Reagent Lane
Fair Lawn, NJ 07410
For information, call: 201-796-7100
Emergency Number: 201-796-7100
For CHEMTREC assistance, call: 800-424-9300
For International CHEMTREC assistance, call: 703-527-3887
|
Section 2 - Composition, Information on Ingredients
|
| CAS# |
Chemical Name |
Percent |
EINECS/ELINCS |
| 77-09-8 |
Phenolphthalein |
100 | 201-004-7 |
|
Section 3 - Hazards Identification
|
EMERGENCY OVERVIEW
Appearance: off-white crystalline powder.
Caution! Possible cancer hazard. May cause cancer
based on animal data. May cause eye, skin, and respiratory tract
irritation. May be harmful if swallowed. The toxicological properties
of this material have not been fully investigated.
Target Organs: None known.
Potential Health Effects
Eye:
May cause eye irritation.
Skin:
May cause skin irritation. May be harmful if absorbed through the
skin.
Ingestion:
Causes gastrointestinal irritation with nausea, vomiting and
diarrhea. Ingestion may cause fever, blood pressure increase and
other unspecified vascular effects.
Major danger of overdosage is fluid and electrolyte deficits
resulting from excessive laxative effect.
Inhalation:
May cause respiratory tract irritation. May be harmful if inhaled.
Chronic:
Possible cancer hazard based on tests with laboratory animals.
|
Section 4 - First Aid Measures
|
Eyes:
In case of contact, immediately flush eyes with plenty of water for a
t least 15 minutes. Get medical aid.
Skin:
In case of contact, flush skin with plenty of water. Remove
contaminated clothing and shoes. Get medical aid if irritation
develops and persists. Wash clothing before reuse.
Ingestion:
If swallowed, do not induce vomiting unless directed to do so by
medical personnel. Never give anything by mouth to an unconscious
person. Get medical aid.
Inhalation:
If inhaled, remove to fresh air. If not breathing, give artificial
respiration. If breathing is difficult, give oxygen. Get medical aid.
Notes to Physician:
Treat symptomatically and supportively.
|
Section 5 - Fire Fighting Measures
|
General Information:
As in any fire, wear a self-contained breathing apparatus in
pressure-demand, MSHA/NIOSH (approved or equivalent), and full
protective gear. During a fire, irritating and highly toxic gases
may be generated by thermal decomposition or combustion. This
material in sufficient quantity and reduced particle size is capable
of creating a dust explosion.
Extinguishing Media:
Use water spray, dry chemical, carbon dioxide, or appropriate foam.
Flash Point: Not available.
Autoignition Temperature: Not available.
Explosion Limits, Lower:Not available.
Upper: Not available.
NFPA Rating:
(estimated) Health: 1; Flammability: 1; Instability: 0
|
Section 6 - Accidental Release Measures
|
General Information: Use proper personal protective equipment as indicated
in Section 8.
Spills/Leaks:
Clean up spills immediately, observing precautions in the Protective
Equipment section. Sweep up, then place into a suitable container for
disposal. Avoid generating dusty conditions. Provide ventilation.
|
Section 7 - Handling and Storage
|
Handling:
Wash thoroughly after handling. Wash thoroughly after handling.
Remove contaminated clothing and wash before reuse. Minimize dust
generation and accumulation. Avoid contact with eyes, skin, and
clothing. Keep container tightly closed. Avoid ingestion and
inhalation. Use only in a chemical fume hood.
Storage:
Store in a tightly closed container. Store in a cool, dry,
well-ventilated area away from incompatible substances.
|
Section 8 - Exposure Controls, Personal Protection
|
Engineering Controls:
Good general ventilation should be sufficient to control airborne
levels. Facilities storing or utilizing this material should be
equipped with an eyewash facility and a safety shower.
Exposure Limits
| Chemical Name |
ACGIH |
NIOSH |
OSHA - Final PELs |
| Phenolphthalein
|
none listed
|
none listed
|
none listed
|
OSHA Vacated PELs:
Phenolphthalein:
No OSHA Vacated PELs are listed for this chemical.
Personal Protective Equipment
Eyes:
Wear appropriate protective eyeglasses or chemical
safety goggles as described by OSHA's eye and face
protection regulations in 29 CFR 1910.133 or European
Standard EN166.
Skin:
Wear appropriate gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin
exposure.
Respirators:
Follow the OSHA respirator regulations found in 29
CFR 1910.134 or European Standard EN 149. Use a
NIOSH/MSHA or European Standard EN 149 approved
respirator if exposure limits are exceeded or if
irritation or other symptoms are experienced.
|
Section 9 - Physical and Chemical Properties
|
Physical State: Crystalline powder
Appearance: off-white
Odor: odorless
pH: Not available.
Vapor Pressure: Negligible.
Vapor Density: Not available.
Evaporation Rate:Negligible.
Viscosity: Not available.
Boiling Point: Not available.
Freezing/Melting Point:258 - 263 deg C
Decomposition Temperature:Not available.
Solubility: Insoluble in water.
Specific Gravity/Density:1.299
Molecular Formula:C20H14O4
Molecular Weight:318.0956
|
Section 10 - Stability and Reactivity
|
Chemical Stability:
Stable under normal temperatures and pressures.
Conditions to Avoid:
Dust generation, excess heat.
Incompatibilities with Other Materials:
Strong oxidizing agents.
Hazardous Decomposition Products:
Carbon monoxide, carbon dioxide.
Hazardous Polymerization: Will not occur.
|
Section 11 - Toxicological Information
|
RTECS#:
CAS# 77-09-8:
SM8380000
LD50/LC50:
Not available.
Carcinogenicity:
CAS# 77-09-8:
- ACGIH:
Not listed.
- California:
carcinogen, initial date 5/15/98
- NTP:
Suspect carcinogen
- IARC:
Group 2B carcinogen
Epidemiology:
Doses associated with fatalities have been 1.8 grams and
0.65-1.3 grams.
Teratogenicity:
No information found
Reproductive Effects:
No information found
Mutagenicity:
No information found
Neurotoxicity:
No information found
Other Studies:
|
Section 12 - Ecological Information
|
No information available.
|
Section 13 - Disposal Considerations
|
Chemical waste generators must determine whether a discarded chemical is classified
as a hazardous waste.
US EPA guidelines for the classification determination are listed in 40 CFR Parts 261.3.
Additionally, waste generators must consult state and local hazardous waste regulations to
ensure complete and accurate classification.
RCRA P-Series: None listed.
RCRA U-Series: None listed.
|
Section 14 - Transport Information
|
| |
US DOT |
Canada TDG |
| Shipping Name: |
Not regulated. |
Not regulated. |
| Hazard Class: |
|
|
| UN Number: |
|
|
| Packing Group: |
|
|
|
Section 15 - Regulatory Information
|
US FEDERAL
TSCA
CAS# 77-09-8 is listed on the TSCA inventory.
Health & Safety Reporting List
None of the chemicals are on the Health & Safety Reporting List.
Chemical Test Rules
None of the chemicals in this product are under a Chemical Test Rule.
Section 12b
None of the chemicals are listed under TSCA Section 12b.
TSCA Significant New Use Rule
None of the chemicals in this material have a SNUR under TSCA.
CERCLA Hazardous Substances and corresponding RQs
None of the chemicals in this material have an RQ.
SARA Section 302 Extremely Hazardous Substances
None of the chemicals in this product have a TPQ.
SARA Codes
CAS # 77-09-8: immediate.
Section 313
No chemicals are reportable under Section 313.
Clean Air Act:
This material does not contain any hazardous air pollutants.
This material does not contain any Class 1 Ozone depletors.
This material does not contain any Class 2 Ozone depletors.
Clean Water Act:
None of the chemicals in this product
are listed as Hazardous Substances under the CWA.
None of the chemicals in this
product are listed as Priority Pollutants under the CWA.
None of the chemicals in this
product are listed as Toxic Pollutants under the CWA.
OSHA:
None of the chemicals in this product
are considered highly hazardous by OSHA.
STATE
CAS# 77-09-8 is not present on
state lists from CA, PA, MN, MA, FL, or NJ.
California Prop 65
The following statement(s) is(are) made in order to comply with
the California Safe Drinking Water Act:
WARNING: This product contains Phenolphthalein, a chemical known to
the state of California to cause cancer.
California No Significant Risk Level:
None of the chemicals in this product are listed.
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols:
XN
Risk Phrases:
R 22 Harmful if swallowed.
R 40 Limited evidence of a carcinogenic effect.
Safety Phrases:
S 36/37 Wear suitable protective clothing and gloves.
S 45 In case of accident or if you feel unwell, seek medical advice
immediately (show the label where possible).
WGK (Water Danger/Protection)
CAS# 77-09-8: 1
Canada - DSL/NDSL
CAS# 77-09-8 is listed on Canada's DSL List.
Canada - WHMIS
This product has a WHMIS classification of D2A.
This product has been classified in accordance with the hazard
criteria of the Controlled Products Regulations and the MSDS
contains all of the information required by those regulations.
Canadian Ingredient Disclosure List
|
Section 16 - Additional Information
|
MSDS Creation Date: 12/12/1997
Revision #7 Date: 9/26/2007
The information above is believed to be accurate and represents the best
information currently available to us. However, we make no warranty of
merchantability or any other warranty, express or implied, with respect to
such information, and we assume no liability resulting from its use. Users
should make their own investigations to determine the suitability of the
information for their particular purposes. In no event shall Fisher be liable
for any claims, losses, or damages of any third party or for lost profits
or any special, indirect, incidental, consequential or exemplary
damages, howsoever arising, even if Fisher has been advised of
the possibility of such damages.
|
|