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Section 1 - Chemical Product and Company Identification |
MSDS Name: Buffer Solution pH 4.63
Catalog Numbers:
SB100-1
Synonyms:
None
Company Identification:
Fisher Scientific
1 Reagent Lane
Fair Lawn, NJ 07410
For information, call: 201-796-7100
Emergency Number: 201-796-7100
For CHEMTREC assistance, call: 800-424-9300
For International CHEMTREC assistance, call: 703-527-3887
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Section 2 - Composition, Information on Ingredients
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| CAS# |
Chemical Name |
Percent |
EINECS/ELINCS |
| 7732-18-5 |
Water |
99.0 | 231-791-2 |
| 6131-90-4 |
Sodium acetate, trihydrate |
0.8 | unlisted |
| 64-19-7 |
Acetic acid |
0.40 | 200-580-7 |
| 50-00-0 |
Formaldehyde |
0.05 | 200-001-8 |
| 67-56-1 |
Methyl alcohol |
0.02 | 200-659-6 |
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Section 3 - Hazards Identification
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EMERGENCY OVERVIEW
Appearance: not available liquid.
Caution! May cause eye, skin, and respiratory
tract irritation.
Target Organs: None.
Potential Health Effects
Eye:
May cause eye irritation.
Skin:
May cause skin irritation.
Ingestion:
May cause irritation of the digestive tract.
Inhalation:
May cause respiratory tract irritation.
Chronic:
Contains formaldehyde which can cause cancer in humans. There is
sufficient evidence that formaldehyde causes nasopharyngeal cancer in
humans, a rare cancer in developed countries.
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Section 4 - First Aid Measures
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Eyes:
Get medical aid. Gently lift eyelids and flush continuously with wate
r.
Skin:
Get medical aid if irritation develops or persists. Flush skin with
plenty of soap and water.
Ingestion:
If victim is conscious and alert, give 2-4 cupfuls of milk or water.
Get medical aid.
Inhalation:
Get medical aid immediately. Remove from exposure and move to fresh
air immediately. If not breathing, give artificial respiration.
Notes to Physician:
Treat symptomatically and supportively.
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Section 5 - Fire Fighting Measures
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General Information:
As in any fire, wear a self-contained breathing apparatus in
pressure-demand, MSHA/NIOSH (approved or equivalent), and full
protective gear.
Extinguishing Media:
Substance is noncombustible; use agent most appropriate to
extinguish surrounding fire.
Flash Point: Not applicable.
Autoignition Temperature: Not applicable.
Explosion Limits, Lower:Not available.
Upper: Not available.
NFPA Rating:
(estimated) Health: 1; Flammability: 0; Instability: 0
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Section 6 - Accidental Release Measures
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General Information: Use proper personal protective equipment as indicated
in Section 8.
Spills/Leaks:
Absorb spill with inert material (e.g. vermiculite, sand or earth),
then place in suitable container.
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Section 7 - Handling and Storage
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Handling:
Use with adequate ventilation. Avoid contact with eyes. Keep
container tightly closed.
Storage:
Store in a cool, dry place.
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Section 8 - Exposure Controls, Personal Protection
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Engineering Controls:
Good general ventilation should be sufficient to control airborne
levels.
Exposure Limits
| Chemical Name |
ACGIH |
NIOSH |
OSHA - Final PELs |
| Water
|
none listed
|
none listed
|
none listed
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| Sodium acetate, trihydrate
|
none listed
|
none listed
|
none listed
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| Acetic acid
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10 ppm TWA; 15 ppm STEL
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10 ppm TWA; 25 mg/m3 TWA 50 ppm IDLH
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10 ppm TWA; 25 mg/m3 TWA
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| Formaldehyde
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0.3 ppm Ceiling
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0.016 ppm TWA 20 ppm IDLH
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0.75 ppm TWA; 0.5 ppm Action Level; 0.75 ppm TWA; 2 ppm STEL (Irritant and potential cancer ha zard - see 29 CFR 1910.1048)
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| Methyl alcohol
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200 ppm TWA; 250 ppm STEL; Skin - potential significant contribution to overall exposure by the cutaneous r oute
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200 ppm TWA; 260 mg/m3 TWA 6000 ppm IDLH
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200 ppm TWA; 260 mg/m3 TWA
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OSHA Vacated PELs:
Water:
No OSHA Vacated PELs are listed for this chemical.
Sodium acetate, trihydrate:
No OSHA Vacated PELs are listed for this chemical.
Acetic acid:
10 ppm TWA; 25 mg/m3 TWA
Formaldehyde:
3 ppm TWA (unless specified in 1910.1048)
Methyl alcohol:
200 ppm TWA; 260 mg/m3 TWA
Personal Protective Equipment
Eyes:
Wear appropriate protective eyeglasses or chemical
safety goggles as described by OSHA's eye and face
protection regulations in 29 CFR 1910.133 or European
Standard EN166.
Skin:
Wear appropriate gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to minimize
contact with skin.
Respirators:
Follow the OSHA respirator regulations found in 29
CFR 1910.134 or European Standard EN 149. Use a
NIOSH/MSHA or European Standard EN 149 approved
respirator if exposure limits are exceeded or if
irritation or other symptoms are experienced.
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Section 9 - Physical and Chemical Properties
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Physical State: Liquid
Appearance: not available
Odor: none reported
pH: 4.63
Vapor Pressure: Not available.
Vapor Density: Not available.
Evaporation Rate:Not available.
Viscosity: Not available.
Boiling Point: 100 deg C
Freezing/Melting Point:0 deg C
Decomposition Temperature:Not available.
Solubility: Soluble in water.
Specific Gravity/Density:1.0
Molecular Formula:Mixture
Molecular Weight:Not available.
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Section 10 - Stability and Reactivity
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Chemical Stability:
Stable.
Conditions to Avoid:
None reported.
Incompatibilities with Other Materials:
None reported.
Hazardous Decomposition Products:
Irritating and toxic gases.
Hazardous Polymerization: Not available.
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Section 11 - Toxicological Information
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RTECS#:
CAS# 7732-18-5:
ZC0110000
CAS# 6131-90-4:
AJ4580000
CAS# 64-19-7:
AF1225000
CAS# 50-00-0:
LP8925000
CAS# 67-56-1:
PC1400000
LD50/LC50:
CAS# 7732-18-5:
Oral, rat: LD50 =
>90 mL/kg;
.
CAS# 6131-90-4:
.
CAS# 64-19-7:
Draize test,
rabbit, skin: 50 mg/24H Mild;
Inhalation, mouse: LC50 = 5620
ppm/1H;
Oral, rat: LD50 = 3310
mg/kg;
Skin, rabbit: LD50 = 1060
uL/kg;
.
CAS# 50-00-0:
Draize test,
rabbit, eye: 750 ug/24H Severe;
Draize test, rabbit, eye: 750 ug
Severe;
Draize test, rabbit, eye:
10 mg Severe;
Draize test, rabbit,
eye: 37% Severe;
Draize test,
rabbit, skin: 2 mg/24H Severe;
Draize test, rabbit, skin: 50 mg/24H
Moderate;
Inhalation, mouse: LC50 =
454 mg/m3/4H;
Inhalation, mouse:
LC50 = 505 mg/m3/2H;
Inhalation,
rat: LC50 = 203 mg/m3;
Inhalation,
rat: LC50 = 578 mg/m3/2H;
Inhalation, rat: LC50 = 250
ppm/2H;
Oral, mouse: LD50 = 42
CAS# 67-56-1:
Draize test,
rabbit, eye: 40 mg Moderate;
Draize
test, rabbit, eye: 100 mg/24H Moderate;
Draize test, rabbit, skin: 20 mg/24H
Moderate;
Inhalation, rabbit: LC50
= 81000 mg/m3/14H;
Inhalation, rat:
LC50 = 64000 ppm/4H;
Oral, mouse:
LD50 = 7300 mg/kg;
Oral, rabbit:
LD50 = 14200 mg/kg;
Oral, rat:
LD50 = 5600 mg/kg;
Skin, rabbit:
LD50 = 15800 mg/kg;
.
Carcinogenicity:
CAS# 7732-18-5:
Not listed by ACGIH, IARC, NTP, or CA Prop 65.
CAS# 6131-90-4:
Not listed by ACGIH, IARC, NTP, or CA Prop 65.
CAS# 64-19-7:
Not listed by ACGIH, IARC, NTP, or CA Prop 65.
CAS# 50-00-0:
- ACGIH:
A2 - Suspected Human Carcinogen
- California:
carcinogen, initial date 1/1/88 (gas)
- NTP:
Suspect carcinogen
- IARC:
Group 1 carcinogen
CAS# 67-56-1:
Not listed by ACGIH, IARC, NTP, or CA Prop 65.
Epidemiology:
~~Methanol has been shown to prooduce fetoxicity in the
embryo or fetus in laboratory animals. Specific
developmental abnormalities include:musculoskeletal,
urogenital and cardiovascular systems,
Teratogenicity:
Effects on the newborn by exposure to formaldehyde have
been reported in rats by inhalation, such as behavioral
effects, biochemical and metabolic effects and reduced
weight gain. Cytological changes were also noted. Specific
developmental abnormalities were reported by the
intraperitoneal route of exposure in mice.
Reproductive Effects:
Paternal effects were reported in male rats by inhalation,
oral ingestion and intraperitoneal injection of
formaldehyde. Organs affected included the prostate,
seminal vesicle, Cowpers gland, urethra, testes, sperm duct
and epididymis. Spermatogenesis was also affected.
Mutagenicity:
No data available.
Neurotoxicity:
No data available.
Other Studies:
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Section 12 - Ecological Information
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Ecotoxicity:
No data available.
No information available.
Environmental:
No information reported.
Physical:
No information available.
Other:
None.
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Section 13 - Disposal Considerations
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Chemical waste generators must determine whether a discarded chemical is classified
as a hazardous waste.
US EPA guidelines for the classification determination are listed in 40 CFR Parts 261.3.
Additionally, waste generators must consult state and local hazardous waste regulations to
ensure complete and accurate classification.
RCRA P-Series: None listed.
RCRA U-Series:
CAS# 50-00-0: waste
number U122.
CAS# 67-56-1: waste number U154
(Ignitable waste).
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Section 14 - Transport Information
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| |
US DOT |
Canada TDG |
| Shipping Name: |
Not regulated as a hazardous material |
No information available. |
| Hazard Class: |
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| UN Number: |
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| Packing Group: |
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Section 15 - Regulatory Information
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US FEDERAL
TSCA
CAS# 7732-18-5 is listed on the TSCA inventory.
CAS# 6131-90-4 is not on the TSCA Inventory because it is a hydrate.
It is considered to be listed if the CAS number for the anhydrous form
is on the inventory (40CFR720.3(u)(2)).
CAS# 64-19-7 is listed on the TSCA inventory.
CAS# 50-00-0 is listed on the TSCA inventory.
CAS# 67-56-1 is listed on the TSCA inventory.
Health & Safety Reporting List
None of the chemicals are on the Health & Safety Reporting List.
Chemical Test Rules
None of the chemicals in this product are under a Chemical Test Rule.
Section 12b
None of the chemicals are listed under TSCA Section 12b.
TSCA Significant New Use Rule
None of the chemicals in this material have a SNUR under TSCA.
CERCLA Hazardous Substances and corresponding RQs
CAS# 64-19-7: 5000 lb final RQ; 2270 kg final RQ
CAS# 50-00-0: 100 lb final RQ; 45.4 kg final RQ
CAS# 67-56-1: 5000 lb final RQ; 2270 kg final RQ
SARA Section 302 Extremely Hazardous Substances
CAS# 50-00-0: 500 lb TPQ
SARA Codes
CAS # 6131-90-4: Not controlled.
CAS # 64-19-7: immediate, delayed, fire.
CAS # 50-00-0: immediate, delayed.
CAS # 67-56-1: immediate, fire.
Section 313
Formaldehyde is not at a high
enough concentration to be reportable under Section 313.
Methyl alcohol is not at a high
enough concentration to be reportable under Section 313.
No chemicals are reportable under Section 313.
Clean Air Act:
CAS# 50-00-0 is listed as a hazardous air pollutant (HAP).
CAS# 67-56-1 is listed as a hazardous air pollutant (HAP).
This material does not contain any Class 1 Ozone depletors.
This material does not contain any Class 2 Ozone depletors.
Clean Water Act:
CAS# 64-19-7 is listed as a Hazardous Substance under the CWA.
CAS# 50-00-0 is listed as a Hazardous Substance under the CWA.
None of the chemicals in this
product are listed as Priority Pollutants under the CWA.
None of the chemicals in this
product are listed as Toxic Pollutants under the CWA.
OSHA:
CAS# 50-00-0 is considered highly hazardous by OSHA.
STATE
CAS# 7732-18-5 is not present on
state lists from CA, PA, MN, MA, FL, or NJ.
CAS# 6131-90-4 is not present on
state lists from CA, PA, MN, MA, FL, or NJ.
CAS# 64-19-7 can be found on the
following state right to know lists: California, New Jersey,
Pennsylvania, Minnesota, Massachusetts.
CAS# 50-00-0 can be found on the
following state right to know lists: California, New Jersey,
Pennsylvania, Minnesota, Massachusetts.
CAS# 67-56-1 can be found on the
following state right to know lists: California, New Jersey,
Pennsylvania, Minnesota, Massachusetts.
California Prop 65
WARNING: This product contains Formaldehyde, a chemical known to the
state of California to cause cancer.
California No Significant Risk Level:
CAS# 50-00-0: 40 鎔/day NSRL
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols:
Not available.
Risk Phrases:
Safety Phrases:
WGK (Water Danger/Protection)
CAS# 7732-18-5: No information available.
CAS# 6131-90-4: 1
CAS# 64-19-7: 1
CAS# 50-00-0: 2
CAS# 67-56-1: 1
Canada - DSL/NDSL
CAS# 7732-18-5 is listed on Canada's DSL List.
CAS# 64-19-7 is listed on Canada's DSL List.
CAS# 50-00-0 is listed on Canada's DSL List.
CAS# 67-56-1 is listed on Canada's DSL List.
Canada - WHMIS
This product has a WHMIS classification of D2B.
This product has been classified in accordance with the hazard
criteria of the Controlled Products Regulations and the MSDS
contains all of the information required by those regulations.
Canadian Ingredient Disclosure List
CAS# 64-19-7 is listed on the Canadian Ingredient Disclosure List.
CAS# 50-00-0 is listed on the Canadian Ingredient Disclosure List.
CAS# 67-56-1 is listed on the Canadian Ingredient Disclosure List.
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Section 16 - Additional Information
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MSDS Creation Date: 6/07/1999
Revision #5 Date: 11/07/2007
The information above is believed to be accurate and represents the best
information currently available to us. However, we make no warranty of
merchantability or any other warranty, express or implied, with respect to
such information, and we assume no liability resulting from its use. Users
should make their own investigations to determine the suitability of the
information for their particular purposes. In no event shall Fisher be liable
for any claims, losses, or damages of any third party or for lost profits
or any special, indirect, incidental, consequential or exemplary
damages, howsoever arising, even if Fisher has been advised of
the possibility of such damages.
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