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MSDS  
:
 Sulfanilamide
CAS  
:
 63-74-1
SYNONYMS  
:
 

Section 1 - Chemical Product and Company Identification

MSDS Name: Sulfanilamide
Catalog Numbers: AC132850000, AC132855000, 13285-1000, O4525-100
Synonyms:
4-Aminobenzenesulfonamide.
Company Identification:

              Fisher Scientific
              1 Reagent Lane
              Fair Lawn, NJ 07410
For information, call:
201-796-7100
Emergency Number:
201-796-7100
For CHEMTREC assistance, call:
800-424-9300
For International CHEMTREC assistance, call:
703-527-3887

Section 2 - Composition, Information on Ingredients

CAS# Chemical Name Percent EINECS/ELINCS
63-74-1 Sulfanilamide 98 200-563-4

Section 3 - Hazards Identification

EMERGENCY OVERVIEW

Appearance: white to almost white crystalline powder.
Warning! Causes eye, skin, and respiratory tract irritation. May cause reproductive and fetal effects.
Target Organs: Blood, spleen, respiratory system, eyes, skin.


Potential Health Effects
Eye: Causes eye irritation.
Skin: Causes skin irritation. May be harmful if absorbed through the skin. Patch test (humans): negative. Sensitization test (guinea pig): negative. (Merck KGaA)
Ingestion: May cause irritation of the digestive tract. May be harmful if swallowed. Used therapeutically in large oral doses, sulfanilamide has produced damage to the liver, the blood system and has caused photosensitive skin reactions. This level of exposure is not likely under conditions of usual commercial or industrial use.
Inhalation: Causes respiratory tract irritation. May be harmful if inhaled.
Chronic: May cause reproductive and fetal effects. Repeated exposure may cause damage to the spleen. Chronic exposure may cause blood effects. Animal studies have reported the development of tumors.

Section 4 - First Aid Measures


Eyes: Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.
Skin: Get medical aid. Immediately flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes.
Ingestion: Do not induce vomiting. Get medical aid.
Inhalation: Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
Notes to Physician: Treat symptomatically and supportively.

Section 5 - Fire Fighting Measures


General Information: As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear.
Extinguishing Media: Use water spray, dry chemical, or carbon dioxide.
Flash Point: Not applicable.
Autoignition Temperature: Not applicable.
Explosion Limits, Lower:Not available.
Upper: Not available.
NFPA Rating: (estimated) Health: 2; Flammability: 1; Instability: 1

Section 6 - Accidental Release Measures


General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks: Vacuum or sweep up material and place into a suitable disposal container. Avoid generating dusty conditions. Provide ventilation. Do not let this chemical enter the environment.

Section 7 - Handling and Storage


Handling: Use with adequate ventilation. Minimize dust generation and accumulation. Do not get in eyes, on skin, or on clothing. Do not ingest or inhale.
Storage: Store in a cool, dry place. Keep containers tightly closed. Store protected from light. Store under an inert atmosphere.

Section 8 - Exposure Controls, Personal Protection


Engineering Controls: Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate ventilation to keep airborne concentrations low.
Exposure Limits
Chemical Name ACGIH NIOSH OSHA - Final PELs
Sulfanilamide none listed none listed none listed

OSHA Vacated PELs: Sulfanilamide: No OSHA Vacated PELs are listed for this chemical.
Personal Protective Equipment
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166.
Skin: Wear appropriate protective gloves to prevent skin exposure.
Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators: A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant respirator use.

Section 9 - Physical and Chemical Properties


Physical State: Crystalline powder
Appearance: white to almost white
Odor: none reported
pH: 5.8 - 6.1 (0.5% aq.sol.)
Vapor Pressure: Negligible
Vapor Density: Not available.
Evaporation Rate:Not applicable.
Viscosity: Not available.
Boiling Point: Not applicable.
Freezing/Melting Point:163 - 167 deg C
Decomposition Temperature:Not available.
Solubility: 7.5 g/L @ (20°C)
Specific Gravity/Density:Not available.
Molecular Formula:C6H8N2O2S
Molecular Weight:172.20

Section 10 - Stability and Reactivity


Chemical Stability: Air sensitive. Light sensitive.
Conditions to Avoid: Incompatible materials, light, dust generation, exposure to air, excess heat.
Incompatibilities with Other Materials: Strong oxidizing agents.
Hazardous Decomposition Products: Carbon monoxide, oxides of nitrogen, oxides of sulfur, carbon dioxide.
Hazardous Polymerization: Has not been reported

Section 11 - Toxicological Information


RTECS#:      
CAS# 63-74-1: WO8400000
LD50/LC50:
CAS# 63-74-1:
     Oral, mouse: LD50 = 3 gm/kg;
     Oral, rabbit: LD50 = 1300 mg/kg;
     Oral, rat: LD50 = 3900 mg/kg;
.

Carcinogenicity:
CAS# 63-74-1: Not listed by ACGIH, IARC, NTP, or CA Prop 65.

Epidemiology: Tumorigenic effects have been reported in experimental animals.
Teratogenicity: Teratogenic effects have occurred in humans.
Reproductive Effects: Adverse reproductive effects have occurred in humans.
Mutagenicity: Mutagenic effects have occurred in experimental animals.
Neurotoxicity: No information found
Other Studies:

Section 12 - Ecological Information


Ecotoxicity: No data available. No information available.
Environmental: No information available.
Physical: No information available.
Other: Do not empty into drains.

Section 13 - Disposal Considerations

Chemical waste generators must determine whether a discarded chemical is classified as a hazardous waste. US EPA guidelines for the classification determination are listed in 40 CFR Parts 261.3. Additionally, waste generators must consult state and local hazardous waste regulations to ensure complete and accurate classification.
RCRA P-Series: None listed.
RCRA U-Series: None listed.

Section 14 - Transport Information

US DOT Canada TDG
Shipping Name: Not regulated. Not regulated.
Hazard Class:
UN Number:
Packing Group:

Section 15 - Regulatory Information

US FEDERAL

TSCA
     CAS# 63-74-1 is listed on the TSCA inventory.
Health & Safety Reporting List
     None of the chemicals are on the Health & Safety Reporting List.
Chemical Test Rules
     None of the chemicals in this product are under a Chemical Test Rule.
Section 12b
     None of the chemicals are listed under TSCA Section 12b.
TSCA Significant New Use Rule
     None of the chemicals in this material have a SNUR under TSCA.
CERCLA Hazardous Substances and corresponding RQs
     None of the chemicals in this material have an RQ.
SARA Section 302 Extremely Hazardous Substances
     None of the chemicals in this product have a TPQ.
SARA Codes
     CAS # 63-74-1: immediate, delayed.
Section 313      No chemicals are reportable under Section 313.
Clean Air Act:
     This material does not contain any hazardous air pollutants.
     This material does not contain any Class 1 Ozone depletors.
     This material does not contain any Class 2 Ozone depletors.
Clean Water Act:
     None of the chemicals in this product are listed as Hazardous Substances under the CWA.
     None of the chemicals in this product are listed as Priority Pollutants under the CWA.
     None of the chemicals in this product are listed as Toxic Pollutants under the CWA.
OSHA:
     None of the chemicals in this product are considered highly hazardous by OSHA.
STATE
     CAS# 63-74-1 is not present on state lists from CA, PA, MN, MA, FL, or NJ.

California Prop 65

California No Significant Risk Level: None of the chemicals in this product are listed.

European/International Regulations

European Labeling in Accordance with EC Directives
Hazard Symbols:
     XI
Risk Phrases:

     R 36/37/38 Irritating to eyes, respiratory system and skin.

Safety Phrases:

     S 26 In case of contact with eyes, rinse immediately with plenty of
     water and seek medical advice.
     S 37/39 Wear suitable gloves and eye/face protection.

WGK (Water Danger/Protection)

     CAS# 63-74-1: 1
Canada - DSL/NDSL
     CAS# 63-74-1 is listed on Canada's DSL List.
Canada - WHMIS
     not available.
This product has been classified in accordance with the hazard criteria of the Controlled Products Regulations and the MSDS contains all of the information required by those regulations.
Canadian Ingredient Disclosure List

Section 16 - Additional Information

MSDS Creation Date: 12/12/1997
Revision #6 Date: 1/24/2008

The information above is believed to be accurate and represents the best information currently available to us. However, we make no warranty of merchantability or any other warranty, express or implied, with respect to such information, and we assume no liability resulting from its use. Users should make their own investigations to determine the suitability of the information for their particular purposes. In no event shall Fisher be liable for any claims, losses, or damages of any third party or for lost profits or any special, indirect, incidental, consequential or exemplary damages, howsoever arising, even if Fisher has been advised of the possibility of such damages.

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