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Search   
MSDS  
:
 Procaine hydrochloride, 99%
CAS  
:
 51-05-8
SYNONYMS  
:
 2-(diethylamino)ethyl ester monochloride; Chlorocaine

Section 1 - Chemical Product and Company Identification
MSDS Name: Procaine hydrochloride, 99%
Catalog Numbers: AC207310000, AC207310050, AC207311000
Synonyms:
2-(Diethylamino)ethyl 4-aminobenzoate; p-Aminobenzoic acid 2-diethylaminoethyl ester hydrochloride; 4-Aminobenzioc acid 2-(diethylamino)ethyl ester hydrochloride; Benzoic acid, 4-amino-, 2-(diethylamino)ethyl ester monochloride; Chlorocaine
Company Identification:

              Acros Organics N.V.
              One Reagent Lane
              Fair Lawn, NJ 07410
For information in North America, call: 800-ACROS-01
For emergencies in the US, call CHEMTREC: 800-424-9300

Section 2 - Composition, Information on Ingredients

CAS# Chemical Name Percent EINECS/ELINCS
51-05-8 Procaine hydrochloride 99 200-077-2

Section 3 - Hazards Identification

EMERGENCY OVERVIEW

Appearance: White Crystalline Powder.
Warning! Harmful if swallowed. May cause eye and skin irritation. May cause respiratory and digestive tract irritation. Light sensitive. Air sensitive.
Target Organs: Nerves.


Potential Health Effects
Eye: May cause eye irritation.
Skin: May cause skin irritation.
Ingestion: Harmful if swallowed. May cause irritation of the digestive tract.
Inhalation: May cause respiratory tract irritation.
Chronic: May cause reproductive and fetal effects. Human systemic effects may include acute renal failure and acute tubular necrosis.

Section 4 - First Aid Measures


Eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.
Skin: Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.
Ingestion: Do not induce vomiting. If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid immediately.
Inhalation: Get medical aid immediately. Remove from exposure and move to fresh air immediately. If breathing is difficult, give oxygen. Do NOT use mouth-to-mouth resuscitation. If breathing has ceased apply artificial respiration using oxygen and a suitable mechanical device such as a bag and a mask.
Notes to Physician: Treat symptomatically and supportively.

Section 5 - Fire Fighting Measures


General Information: As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion.
Extinguishing Media: Use agent most appropriate to extinguish fire. Use water spray, dry chemical, carbon dioxide, or appropriate foam.
Flash Point: Not available.
Autoignition Temperature: Not available.
Explosion Limits, Lower:Not available.
Upper: Not available.
NFPA Rating: (estimated) Health: 2; Flammability: 0; Instability: 0

Section 6 - Accidental Release Measures


General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks: Clean up spills immediately, observing precautions in the Protective Equipment section. Sweep up or absorb material, then place into a suitable clean, dry, closed container for disposal. Avoid generating dusty conditions. Provide ventilation. Place under an inert atmosphere.

Section 7 - Handling and Storage


Handling: Wash thoroughly after handling. Use only in a well-ventilated area. Minimize dust generation and accumulation. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Do not ingest or inhale. Store protected from light. Handle under an inert atmosphere. Store protected from air. Wash clothing before reuse.
Storage: Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. Do not expose to air. Store protected from light. Store under an inert atmosphere.

Section 8 - Exposure Controls, Personal Protection


Engineering Controls: Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate ventilation to keep airborne concentrations low.
Exposure Limits
Chemical Name ACGIH NIOSH OSHA - Final PELs
Procaine hydrochloride none listed none listed none listed

OSHA Vacated PELs: Procaine hydrochloride: No OSHA Vacated PELs are listed for this chemical.
Personal Protective Equipment
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166.
Skin: Wear appropriate protective gloves to prevent skin exposure.
Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators: A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant respirator use.

Section 9 - Physical and Chemical Properties


Physical State: Crystalline powder
Appearance: White Crystalline Powder
Odor: None reported.
pH: Not available.
Vapor Pressure: Not available.
Vapor Density: Not available.
Evaporation Rate:Not available.
Viscosity: Not available.
Boiling Point: Not available.
Freezing/Melting Point:155.00 - 156.00 deg C
Decomposition Temperature:Not available.
Solubility: Soluble.
Specific Gravity/Density:Not available.
Molecular Formula:C13H20N2O2.HCl
Molecular Weight:272.77

Section 10 - Stability and Reactivity


Chemical Stability: Air sensitive. Sensitive to light.
Conditions to Avoid: Incompatible materials, light, dust generation, exposure to air, strong oxidants.
Incompatibilities with Other Materials: Strong oxidizing agents.
Hazardous Decomposition Products: Hydrogen chloride, nitrogen oxides, carbon monoxide, carbon dioxide, nitrogen.
Hazardous Polymerization: Has not been reported.

Section 11 - Toxicological Information


RTECS#:      
CAS# 51-05-8: DG2275000
LD50/LC50:
CAS# 51-05-8:
     Oral, mouse: LD50 = 175 mg/kg;
     Oral, rat: LD50 = 200 mg/kg;
.
Multiple routes: Human, man TDLo = 2286
Carcinogenicity:
CAS# 51-05-8: Not listed by ACGIH, IARC, NTP, or CA Prop 65.

Epidemiology: No information available.
Teratogenicity: No information available.
Reproductive Effects: May cause reproductive effects in humans.
Mutagenicity: No information available.
Neurotoxicity: No information available.
Other Studies:

Section 12 - Ecological Information

No information available.

Section 13 - Disposal Considerations

Chemical waste generators must determine whether a discarded chemical is classified as a hazardous waste. US EPA guidelines for the classification determination are listed in 40 CFR Parts 261.3. Additionally, waste generators must consult state and local hazardous waste regulations to ensure complete and accurate classification.
RCRA P-Series: None listed.
RCRA U-Series: None listed.

Section 14 - Transport Information

US DOT Canada TDG
Shipping Name: TOXIC SOLIDS, ORGANIC, N.O.S. TOXIC SOLID ORGANIC, NOS (PROCAINE HYDROCHLORIDE)
Hazard Class: 6.1 6.1
UN Number: UN2811 UN2811
Packing Group: III III

Section 15 - Regulatory Information

US FEDERAL

TSCA
     CAS# 51-05-8 is listed on the TSCA inventory.
Health & Safety Reporting List
     None of the chemicals are on the Health & Safety Reporting List.
Chemical Test Rules
     None of the chemicals in this product are under a Chemical Test Rule.
Section 12b
     None of the chemicals are listed under TSCA Section 12b.
TSCA Significant New Use Rule
     None of the chemicals in this material have a SNUR under TSCA.
CERCLA Hazardous Substances and corresponding RQs
     None of the chemicals in this material have an RQ.
SARA Section 302 Extremely Hazardous Substances
     None of the chemicals in this product have a TPQ.
Section 313      No chemicals are reportable under Section 313.
Clean Air Act:
     This material does not contain any hazardous air pollutants.
     This material does not contain any Class 1 Ozone depletors.
     This material does not contain any Class 2 Ozone depletors.
Clean Water Act:
     None of the chemicals in this product are listed as Hazardous Substances under the CWA.
     None of the chemicals in this product are listed as Priority Pollutants under the CWA.
     None of the chemicals in this product are listed as Toxic Pollutants under the CWA.
OSHA:
     None of the chemicals in this product are considered highly hazardous by OSHA.
STATE
     CAS# 51-05-8 is not present on state lists from CA, PA, MN, MA, FL, or NJ.

California Prop 65

California No Significant Risk Level: None of the chemicals in this product are listed.

European/International Regulations

European Labeling in Accordance with EC Directives
Hazard Symbols:
     T
Risk Phrases:

     R 25 Toxic if swallowed.

Safety Phrases:

     S 45 In case of accident or if you feel unwell, seek medical advice
     immediately (show the label where possible).

WGK (Water Danger/Protection)

     CAS# 51-05-8: 1
Canada - DSL/NDSL
     CAS# 51-05-8 is listed on Canada's DSL List.
Canada - WHMIS
     This product has a WHMIS classification of D1B.
This product has been classified in accordance with the hazard criteria of the Controlled Products Regulations and the MSDS contains all of the information required by those regulations.
Canadian Ingredient Disclosure List

Section 16 - Additional Information

MSDS Creation Date: 12/07/1998
Revision #3 Date: 10/03/2005

The information above is believed to be accurate and represents the best information currently available to us. However, we make no warranty of merchantability or any other warranty, express or implied, with respect to such information, and we assume no liability resulting from its use. Users should make their own investigations to determine the suitability of the information for their particular purposes. In no event shall Fisher be liable for any claims, losses, or damages of any third party or for lost profits or any special, indirect, incidental, consequential or exemplary damages, howsoever arising, even if Fisher has been advised of the possibility of such damages.

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