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MSDS  
:
 Quinine, anhydrous, 99% (titr)
CAS  
:
 130-95-0
SYNONYMS  
:
 

Section 1 - Chemical Product and Company Identification

MSDS Name: Quinine, anhydrous, 99% (titr)
Catalog Numbers: AC163700000, AC163700100, AC163700250, AC163700500, AC9907459, NC9373663, XXAC16370-4KG, XXAC16370-5K
Synonyms:

Company Identification:

              Fisher Scientific
              1 Reagent Lane
              Fair Lawn, NJ 07410
For information, call:
201-796-7100
Emergency Number:
201-796-7100
For CHEMTREC assistance, call:
800-424-9300
For International CHEMTREC assistance, call:
703-527-3887

Section 2 - Composition, Information on Ingredients

CAS# Chemical Name Percent EINECS/ELINCS
130-95-0 Quinine, anhydrous 99.0 205-003-2

Section 3 - Hazards Identification

EMERGENCY OVERVIEW

Appearance: white to off-white powder.
Warning! Causes eye and skin irritation. May cause allergic skin reaction. May be harmful if swallowed. May cause respiratory tract irritation. May cause central nervous system depression. Light sensitive. May cause kidney damage. May cause loss of hearing. May cause blurred vision. May cause adverse reproductive effects based upon animal studies.
Target Organs: Respiratory system, gastrointestinal system, cardiovascular system, eyes, nervous system, skin.


Potential Health Effects
Eye: Causes eye irritation. Contact with the eyes causes eyes to become swollen, watery, and exude a sticky viscous liquid which forms yellowish crusts. Causes visual disturbances including: blurred vision, disturbed color perception, photophobia, diplopia, night blindness, constricted visual fields, mydriasis, and possibly blindness.
Skin: Causes skin irritation. May cause allergic contact dermatitis.
Ingestion: May cause gastrointestinal irritation with nausea, vomiting and diarrhea. May cause kidney damage. May cause central nervous system depression, characterized by excitement, followed by headache, dizziness, drowsiness, and nausea. Advanced stages may cause collapse, unconsciousness, coma and possible death due to respiratory failure. Ingestion may produce visual and hearing disturbances. Human systemic effects by ingestion may include: visual field changes, tinnitus, and nausea or vomiting.
Inhalation: May cause respiratory tract irritation.
Chronic: Chronic ingestion may cause effects similar to those of acute ingestion.

Section 4 - First Aid Measures


Eyes: Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid imme diately.
Skin: Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes.
Ingestion: If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid immediately.
Inhalation: Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
Notes to Physician: Treat symptomatically.

Section 5 - Fire Fighting Measures


General Information: As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear.
Extinguishing Media: Use agent most appropriate to extinguish fire.
Flash Point: Not available.
Autoignition Temperature: Not available.
Explosion Limits, Lower:Not available.
Upper: Not available.
NFPA Rating: (estimated) Health: 2; Flammability: 0; Instability: 0

Section 6 - Accidental Release Measures


General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks: Sweep up, then place into a suitable container for disposal. Avoid generating dusty conditions.

Section 7 - Handling and Storage


Handling: Wash thoroughly after handling. Use only in a well-ventilated area. Minimize dust generation and accumulation. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation.
Storage: Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. Store below 40C.

Section 8 - Exposure Controls, Personal Protection


Engineering Controls: Use adequate general or local exhaust ventilation to keep airborne concentrations below the permissible exposure limits.
Exposure Limits
Chemical Name ACGIH NIOSH OSHA - Final PELs
Quinine, anhydrous none listed none listed none listed

OSHA Vacated PELs: Quinine, anhydrous: No OSHA Vacated PELs are listed for this chemical.
Personal Protective Equipment
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166.
Skin: Wear appropriate protective gloves to prevent skin exposure.
Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators: Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced.

Section 9 - Physical and Chemical Properties


Physical State: Powder
Appearance: white to off-white
Odor: odorless
pH: Not available.
Vapor Pressure: Not available.
Vapor Density: Not available.
Evaporation Rate:Not available.
Viscosity: Not available.
Boiling Point: Not available.
Freezing/Melting Point:173.00 - 175.00 deg C
Decomposition Temperature:Not available.
Solubility: slightly soluble
Specific Gravity/Density:Not available.
Molecular Formula:C20H24N2O2
Molecular Weight:324.41

Section 10 - Stability and Reactivity


Chemical Stability: Stable under normal temperatures and pressures. May discolor on exposure to light.
Conditions to Avoid: Light, dust generation, temperatures above 40C.
Incompatibilities with Other Materials: Strong oxidizing agents - light.
Hazardous Decomposition Products: Nitrogen oxides, carbon monoxide, carbon dioxide.
Hazardous Polymerization: Has not been reported.

Section 11 - Toxicological Information


RTECS#:      
CAS# 130-95-0: VA6020000
LD50/LC50:
Not available.

Carcinogenicity:
CAS# 130-95-0: Not listed by ACGIH, IARC, NTP, or CA Prop 65.

Epidemiology: No data available.
Teratogenicity: No data available.
Reproductive Effects: No data available.
Mutagenicity: No data available.
Neurotoxicity: No data available.
Other Studies:

Section 12 - Ecological Information

No information available.

Section 13 - Disposal Considerations

Chemical waste generators must determine whether a discarded chemical is classified as a hazardous waste. US EPA guidelines for the classification determination are listed in 40 CFR Parts 261.3. Additionally, waste generators must consult state and local hazardous waste regulations to ensure complete and accurate classification.
RCRA P-Series: None listed.
RCRA U-Series: None listed.

Section 14 - Transport Information

US DOT Canada TDG
Shipping Name: Not regulated as a hazardous material No information available.
Hazard Class:
UN Number:
Packing Group:

Section 15 - Regulatory Information

US FEDERAL

TSCA
     CAS# 130-95-0 is listed on the TSCA inventory.
Health & Safety Reporting List
     None of the chemicals are on the Health & Safety Reporting List.
Chemical Test Rules
     None of the chemicals in this product are under a Chemical Test Rule.
Section 12b
     None of the chemicals are listed under TSCA Section 12b.
TSCA Significant New Use Rule
     None of the chemicals in this material have a SNUR under TSCA.
CERCLA Hazardous Substances and corresponding RQs
     None of the chemicals in this material have an RQ.
SARA Section 302 Extremely Hazardous Substances
     None of the chemicals in this product have a TPQ.
Section 313      No chemicals are reportable under Section 313.
Clean Air Act:
     This material does not contain any hazardous air pollutants.
     This material does not contain any Class 1 Ozone depletors.
     This material does not contain any Class 2 Ozone depletors.
Clean Water Act:
     None of the chemicals in this product are listed as Hazardous Substances under the CWA.
     None of the chemicals in this product are listed as Priority Pollutants under the CWA.
     None of the chemicals in this product are listed as Toxic Pollutants under the CWA.
OSHA:
     None of the chemicals in this product are considered highly hazardous by OSHA.
STATE
     CAS# 130-95-0 can be found on the following state right to know lists: Massachusetts.

California Prop 65

California No Significant Risk Level: None of the chemicals in this product are listed.

European/International Regulations

European Labeling in Accordance with EC Directives
Hazard Symbols:
      Not available.
Risk Phrases:


Safety Phrases:

     S 22 Do not breathe dust.
     S 36 Wear suitable protective clothing.

WGK (Water Danger/Protection)

     CAS# 130-95-0: 1
Canada - DSL/NDSL
     CAS# 130-95-0 is listed on Canada's DSL List.
Canada - WHMIS
     This product has a WHMIS classification of D2B.
This product has been classified in accordance with the hazard criteria of the Controlled Products Regulations and the MSDS contains all of the information required by those regulations.
Canadian Ingredient Disclosure List

Section 16 - Additional Information

MSDS Creation Date: 9/02/1997
Revision #5 Date: 3/16/2007

The information above is believed to be accurate and represents the best information currently available to us. However, we make no warranty of merchantability or any other warranty, express or implied, with respect to such information, and we assume no liability resulting from its use. Users should make their own investigations to determine the suitability of the information for their particular purposes. In no event shall Fisher be liable for any claims, losses, or damages of any third party or for lost profits or any special, indirect, incidental, consequential or exemplary damages, howsoever arising, even if Fisher has been advised of the possibility of such damages.

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2-{4-[3-Chloro-5-(trifluoromethyl)-2-pyridyl]piperazino}ethan-1-ol 215434-40-5
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4-Methyl-2-pyrid-4-yl-1,3-thiazole-5-carbaldehyde 892502-19-1
N-Methyl-(3-phenylisoxazol-5-yl)methylamine 852431-00-6
6-(Tetrahydropyran-4-yloxy)nicotinaldehyde 910036-95-2
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Citrus Burst? 2 Not available
2-Hydroxyphenylboronic acid 89466-08-0
2-(Methylthio)phenylboronic acid 168618-42-6
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3,5-Dichlorophenyl isothiocyanate 6590-93-8
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Quinine, anhydrous, 99% (titr) 130-95-0
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1,2,3,4,6,7-Hexabromonaphthalene na
N-[3-(4-Chloroanilino)-1H-1,2,4-triazol-5-yl]-N'-isopropylurea na
N-[3-(4-Chloroanilino)-1H-1,2,4-triazol-5-yl]-N'-propylurea na
2-Phenylpyrrolidine 1006-64-0
Methyl 2,3-diaminobenzoate 107582-20-7
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5-Bromopicolinic acid 30766-11-1
2-Methoxy-4-vinylphenol 7786-61-0
1-(Thien-2-ylmethyl)piperidine-4-carboxylic acid hydrochloride hydrate 944450-84-4
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2-Bromo-1-(1-methyl-1H-benzimidazol-5-yl)ethanone hydrobromide 944450-78-6
2-Fluoro-4-picoline 461-87-0
N-Methyl-[(4-bromothien-3-yl)methyl]amine hydrochloride 944450-82-2
2-[1-Methyl-3-(trifluoromethyl)-1H-pyrazol-5-yl]benzylamine 910095-35-1
2,5-Bis(trifluoromethyl)benzaldehyde 395-64-2
(4-Thien-2-yltetrahydropyran-4-yl)methylamine 906422-74-0
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5-Nitro-2-furaldehyde, 99% 698-63-5
Ethyl 2,3-dibromo-3-phenylpropanoate 5464-70-0
1-(3-Chloro-4-hydroxyphenyl)propan-1-one 2892-27-5



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